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How does diabetes affect microvascular (small) vessels and macrovascular (large) vessels?
Robert Henry, MD
University of California, San Diego, San Diego, CA

Date Added: 07/03/13

The very small vessels that feed the back of the eye, the nerves, and the kidney. Again, those vessels appear to be particularly susceptible to high glucose levels. With an individual with diabetes who does not take care of their glucose levels very well that is going to put them at increased risk o...
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Dr. Robert Henry's research interests involve studies in the etiology, treatment, and prevention of obesity and type 2 diabetes. Studies are directed almost exclusively at the role of skeletal muscle in these disorders and are designed to elucidate what aspects of muscle metabolism are primary and which are secondary in etiology. These investigations involve studies of intact humans, combining glucose clamps with indirect calorimetry, leg blood flow and substrate balance, and needle biopsies of vastus lateralis muscle. Complementary in vitro studies are performed on human muscle cultures from such patients and involve studies of insulin signal transduction, gene regulation, enzymatic activation, and mitogenesis.
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